NeuroSpring has been at this for a while, and we've completed several interesting research projects since we were founded in 2005.  Take a look at some of our favorites.


The Haptoglobin - Vasospasm ProjectHaptoglobin Vasospasm IP review

Cerebral artery vasospasm is a constriction of brain arteries developing several days after subarachnoid hemorrhage.  Vasospasm is the primary cause of morbidity and mortality in subarachnoid hemorrhage patients who survive the initial hemorrhage.  Support by an American Heart Association grant, NeuroSpring's research found a protein in the blood - haptoglobin - to be the strongest risk factor for predicting the development of vasospasm in subarachnoid hemorrhage patients.

Published Results          Unpublished Results



The Ouabain - Pseudotumor ProjectSodium potassium pump and diffusion v2

Pseudotumor cerebri (also known as idiopathic intracranial hypertension) is a headache condition that often damages the vision.  Caused by an increase in pressure inside the skull, pseudotumor was previous not known to have a cause.  With support from the National Headache Foundation, NeuroSpring was first to discover a link between levels of the steroid, ouabain, and pseudotumor cerebri.

Published Results          Unpublished Results



The Glucocorticoid - Traumatic Brain Injury Project640px Concussion Anatomy

A family of steroids known as glucocorticoids has often been studied as a possible therapy for traumatic brain injury patients, but with conflicting and confusing results.  NeuroSpring evaluated the literature, and its findings suggest that glucocorticoids may be effective but only in certain types of traumatic brain injury patients. 

Published Results



The Insula Stroke ProjectSmoking insula

Previous research has suggested that stroke in a certain part of the brain called the insula cortex are particularly dangerous because it affects cardiac function.  NeuroSpring's research indicates that the association between stroke in the insula and poor outcomes is not so straightforward as previously believed.

Published Results


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